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N216
Sigma
Monoclonal Anti-Na+/Ca+ Exchanger antibody produced in mouse
clone C2C12, ascites fluid
| MDL number: | MFCD01865491 |
Description
| Immunogen | dog cardiac Na+/Ca2+ exchanger. The epitope is in the region of amino acids 371-525, which is on the intracellular side of the plasma membrane. |
| Specificity | The antibody reacts specifically with Na+/Ca2+ exchanger in kidney and cardiac tissues. By immunohistology, staining of the plasma membrane and intense staining of the cardiac T-tubular membrane is observed. The antibody is not recommended for immunoblotting of rat tissues. |
| Physical form | Solution in phosphate buffered saline containing 0.05% sodium azide. |
Properties
| antibody form | ascites fluid |
| clone | C2C12 (monoclonal) |
| mol wt | antigen mol wt 120 kDa (mature exchanger) |
| antigen mol wt 160 kDa (non-reduced) | |
| antigen mol wt 70 kDa (proteolytic fragment) | |
| species reactivity | rat, human, guinea pig, canine, rabbit |
| application(s) | immunoblotting: 1:1,000 |
| immunohistochemistry (frozen sections): 1:200 | |
| immunoprecipitation: suitable | |
| isotype | IgM |
| Gene Information | human ... SLC8A1(6546) |
| shipped in | dry ice |
| storage temp. | −20°C |
Safety
| WGK Germany | NWG |
References
| reference | Frank, J.S., et al., Distribution of the Na+-Ca2+ exchange protein in mammalian cardiac myocytes: an immunofluorescence and immunocolloidal gold-labeling study. J. Cell Biol. 117, 337-345, (1992) Abstract |
